1. Identification of Urine Samples of Healthy Subjects and Breast/Colorectal Cancer Patients through a Comprehensive Analysis of Urine Metabolite
With a view to establishing technologies that will enable anyone to easily take a cancer test, Hitachi is promoting a study on basic technologies for new cancer tests using urine samples.
Recently, Hitachi has successfully developed basic technologies that enable users to identify the urine samples of healthy subjects, breast cancer patients, and colorectal cancer patients through a comprehensive analysis of urine metabolite. More than 1,300 metabolisms, including sugar and lipids, were detected in urine samples, which were narrowed down to around 10 biomarker candidates that help identify the urine samples of cancer patients. The urine of cancer patients was distinguished from that of healthy subjects based on the difference in the amount of the specified biomarker ingredients found.
From here on, Hitachi will further investigate the relationship between cancers and candidate substances for biomarkers and undertake research to distinguish cancer types other than breast and colorectal cancer, as well as putting the technology to practical use.
These results were obtained in collaboration with Summit Pharmaceuticals International Corporation in the acceleration of transformative research for medical innovation by the Japan Agency for Medical Research and Development.